ProTx II (TFA)

MedChem Express

ProTx II (TFA)

14

99.72

ProTx II TFA is a selective blocker of Nav1.7 sodium channels with an IC 50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. ProTx-II inhibits sodium channels by decreasing channel conductance and shifting activation to more positive potentials and blocks action potential propagation in nociceptors [1] [2] .

-20°C,-80°C

12352202