ProTx-III
HY-P5153
Molecular Weight3802.40
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameProTx-III
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC162H246N52O43S6
- Molecular Weight3802.40
- Scientific DescriptionProTx-III is a selective and potent inhibitor of voltage-gated sodium channel Nav1.7, with an IC50 of 2.1 nM. ProTx-III is a spider venom peptide isolated from the venom of the Peruvian green velvet tarantella. ProTx-III has a typical inhibitor cystine knot motif (ICK). ProTx-III is able to reverse the pain response. ProTx-III can be used to study diseases such as chronic pain, epilepsy, and arrhythmia[1].
- SMILESO=C([C@@H](N)CC(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CSSC[C@H](NC3=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)[C@H](CC)C)=O)CC4=CNC=N4)=O)CC(C)C)=O)CCCCN)=O
- UNSPSC12352200