Bio-Connect

ProTx-III

Research Use Only
HY-P5153
MedChem Express
Molecular Weight3802.40
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ProTx-III
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C162H246N52O43S6
  • Molecular Weight
    3802.40
  • Scientific Description
    ProTx-III is a selective and potent inhibitor of voltage-gated sodium channel Nav1.7, with an IC50 of 2.1 nM. ProTx-III is a spider venom peptide isolated from the venom of the Peruvian green velvet tarantella. ProTx-III has a typical inhibitor cystine knot motif (ICK). ProTx-III is able to reverse the pain response. ProTx-III can be used to study diseases such as chronic pain, epilepsy, and arrhythmia[1].
  • SMILES
    O=C([C@@H](N)CC(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CSSC[C@H](NC3=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)[C@H](CC)C)=O)CC4=CNC=N4)=O)CC(C)C)=O)CCCCN)=O
  • UNSPSC
    12352200