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Prox1 antibody

GTX128354
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityZebra Fish
Targetprox1a
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Overview

  • Supplier
    GeneTex
  • Product Name
    Prox1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-Wm: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.95 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID30679
  • Target name
    prox1a
  • Target description
    prospero homeobox 1a
  • Target synonyms
    pr; prospero homeobox protein 1; prospero homeobox protein 1a; prospero-related homeobox gene 1; prospero-related homeobox gene 1a; prox1; zgc:111888
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.
  • Reactivity
    Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Temporospatial inhibition of Erk signaling is required for lymphatic valve formation.
    Read more
  • Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network.
    Read more
  • Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling.
    Read more
  • Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina.
    Read more
  • Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. Ahmed M et al., 2022 Mar 22, Elife
    Read more
  • Noncanonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish. Lei D et al., 2021 Nov 19, iScience
    Read more
  • Intrahepatic cholangiocyte regeneration from an Fgf-dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome. Zhao C et al., 2022 Mar, Hepatology
    Read more
  • Lysyl hydroxylase 3 is required for normal lens capsule formation and maintenance of lens epithelium integrity and fate. Taler K et al., 2020 Feb 15, Dev Biol
    Read more
  • Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish. Mochizuki T et al., 2018 Oct 15, Development
    Read more