PSA antibody [KLK3/1248]

GeneTex

PSA antibody [KLK3/1248]

9

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. This MAb makes an excellent pair wit

IHC-P: 1-2microg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

KLK3/1248

0.2 mg/ml

Unconjugated

KLK3

kallikrein related peptidase 3

APS; gamma-seminoprotein; hK3; kallikrein-3; KLK2A1; P-30 antigen; prostate-specific antigen; PSA; semenogelase; seminin

Mouse

IgG1

Prostate-specific antigen

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203