PSMD7 Polyclonal Antibody

Reddot Biotech

PSMD7 Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

PSMD7

proteasome 26S subunit, non-ATPase 7

26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit rpn8; 26S proteasome regulatory subunit S12; Moloney leukemia virus-34 proviral integration; MOV34; Mov34 homolog; P40; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog); proteasome subunit p40; Rpn8; S12

Rabbit

IgG

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Human, Mouse

-20°C

12352203