PSME3 Antibody, Biotin conjugated

Cusabio

PSME3 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

PSME3

proteasome activator subunit 3

11S regulator complex gamma subunit; 11S regulator complex subunit gamma; activator of multicatalytic protease subunit 3; epididymis secretory protein Li 283; HEL-S-283; Ki; Ki antigen; Ki nuclear autoantigen; PA28 gamma variant 5; PA28G; PA28gamma; PA28-gamma; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki); proteasome activator 28 subunit gamma; proteasome activator 28-gamma; proteasome activator complex subunit 3; REG gamma-3; REG-GAMMA

Rabbit

IgG

Proteasome activator complex subunit 3

Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.

Human

-20°C or -80°C

12352203