PT-ttpy

MedChem Express

PT-ttpy

9

Research Use Only

C22H17Cl2N3Pt

589.38

Pt-ttpy, a metallo-organic complex and potent G-quadruplex ligand, effectively triggers substantial telomere-related DNA damage in cancer cells by inhibiting telomerase and/or telomere functions, while also causing various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

[Cl-][Pt+2]12[N]3=C(C4=CC(C5=CC=C(C)C=C5)=CC(C6=[N]2C=CC=C6)=[N]41)C=CC=C3.[Cl-]

12352200