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PT109

Research Use Only
HY-167832
MedChem Express
Molecular Weight429.64
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PT109
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C23H31N3OS2
  • Molecular Weight
    429.64
  • Scientific Description
    PT109 is a multi-kinase inhibitor. PT109 inhibits JNK (JNK1: IC50=0.143 microM; JNK2: IC50=0.831 microM; JNK3: IC50=0.285 microM) or other kinases (SGK1: IC50=1.34 microM; SGK2: IC50=5.6 microM; SGK3: IC50=26.4 microM; ROCK2: IC50=34 microM) and plays an important role in anti-inflammation, anti-oxidation, neurogenesis, synaptogenesis, etc. In addition, PT109 also reprograms glioblastoma multiforme (GBM) into oligodendrocytes through the PTBP1/PKM1/2 pathway and changes the metabolic pattern of GBM, exerting anti-glioma activity[1][2].
  • SMILES
    O=C(CCCCC1SSCC1)NC2CCC(CC2)NC3=CC=CC4=C3C=CN=C4
  • UNSPSC
    12352200