PTC596
S8820
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NamePTC596
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionUnesbulin (PTC596) is a second-generation BMI-1 inhibitor that accelerates BMI-1 degradation. PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis. IC50 values at 72 hours ranged from 68 to 340 nM in mantle cell lymphoma (MCL) cell lines.
- UNSPSC12352200