PTF1A Antibody

Cusabio

PTF1A Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

PTF1A

pancreas associated transcription factor 1a

PACA, PAGEN2, PTF1-p48, bHLHa29, p48, pancreas transcription factor 1 subunit alpha, bHLH transcription factor p48, class A basic helix-loop-helix protein 29, class II bHLH protein PTF1A, exocrine pancreas-specific transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, pancreas specific transcription factor, 1a

Rabbit

IgG

Pancreas transcription factor 1 subunit alpha

Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5-CANNTG-3. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.

Human, Mouse, Rat

-20°C or -80°C

41116161