
Western Blot Positive WB detected in: U-87 whole cell lysate All lanes: COX2 Antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69 kDa Observed band size: 69 kDa
PTGS2 Recombinant Monoclonal Antibody
CSB-RA920283A0HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPTGS2
Overview
- SupplierCusabio
- Product NamePTGS2 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10B2
- ConjugateUnconjugated
- Gene ID5743
- Target namePTGS2
- Target descriptionprostaglandin-endoperoxide synthase 2
- Target synonymsCOX2; COX-2; cyclooxygenase 2; cyclooxygenase 2b; GRIPGHS; hCox-2; PGG/HS; PGH synthase 2; PGHS-2; PHS II; PHS-2; prostaglandin G/H synthase 2; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- IsotypeIgG
- Protein IDP35354
- Protein NameProstaglandin G/H synthase 2
- Scientific DescriptionConverts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203