PTN Antibody
CSB-PA10239A0RB
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPTN
Overview
- SupplierCusabio
- Product NamePTN Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5764
- Target namePTN
- Target descriptionpleiotrophin
- Target synonymsHARP; HBBM; HB-GAM; HBGF8; HBGF-8; HBNF; HBNF-1; heparin affin regulatory protein; heparin-binding brain mitogen; heparin-binding growth factor 8; heparin-binding growth-associated molecule; heparin-binding neurite outgrowth promoting factor; heparin-binding neurite outgrowth-promoting factor 1; NEGF1; OSF-1; osteoblast-specific factor 1; pleiotrophin; pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
- HostRabbit
- IsotypeIgG
- Protein IDP21246
- Protein NamePleiotrophin
- Scientific DescriptionSecreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203