PTP1B-IN-21

MedChem Express

PTP1B-IN-21

10

Research Use Only

C22H22O11

462.4

PTP1B-IN-21 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.56 microM) over the highly homologous T-cell protein tyrosine phosphatase (TCPTP; IC50>100 microM), which is a key target for type 2 diabetes inhibition.

COC1=CC2=C(C(C3=C(C2=O)C=C(C(CO)=C3O)O[C@H]4[C@H](O)[C@H]([C@@H]([C@H](O4)CO)O)O)=O)C=C1

See Manual

12352200