PTP4A2 Polyclonal Antibody

Reddot Biotech

PTP4A2 Polyclonal Antibody

5

1 mg/ml

PTP4A2

protein tyrosine phosphatase 4A2

HH13; HH7-2; HU-PP-1; OV-1; phosphatase of regenerating liver 2; PRL2; PRL-2; protein tyrosine phosphatase IVA; protein tyrosine phosphatase IVA2; protein tyrosine phosphatase type IVA 2; protein tyrosine phosphatase type IVA, member 2; protein-tyrosine phosphatase of regenerating liver 2; PTP(CAAXII); PTP4A; PTPCAAX2; ptp-IV1a; ptp-IV1b

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

-20°C

12352203