PTP4A3 antibody [N1C3]
GTX100600
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Zebra Fish
TargetPTP4A3
Overview
- SupplierGeneTex
- Product NamePTP4A3 antibody [N1C3]
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID11156
- Target namePTP4A3
- Target descriptionprotein tyrosine phosphatase 4A3
- Target synonymsPRL-3, PRL-R, PRL3, protein tyrosine phosphatase type IVA 3, phosphatase of regenerating liver 3, potentially prenylated protein tyrosine phosphatase, protein tyrosine phosphatase type IVA, member 3, protein-tyrosine phosphatase of regenerating liver 3
- HostRabbit
- IsotypeIgG
- Protein IDO75365
- Protein NameProtein tyrosine phosphatase type IVA 3
- Scientific DescriptionThe protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq]
- ReactivityHuman, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Smith CN, Kihn K, Williamson ZA, et al. Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3. PLoS One. 2023,18(5):e0285964. doi: 10.1371/journal.pone.0285964Read this paper
- Li CJ, Tsai HW, Chen YL, et al. Cisplatin or Doxorubicin Reduces Cell Viability via the PTPIVA3-JAK2-STAT3 Cascade in Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2023,10:123-138. doi: 10.2147/JHC.S385238Read this paper



