
Western Blot Positive WB detected in: PC-3 whole cell lysate, THP-1 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, U87 whole cell lysate All lanes: PTPN1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa
PTPN1 Recombinant Monoclonal Antibody
CSB-RA272100A0HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPTPN1
Overview
- SupplierCusabio
- Product NamePTPN1 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1G3
- ConjugateUnconjugated
- Gene ID5770
- Target namePTPN1
- Target descriptionprotein tyrosine phosphatase non-receptor type 1
- Target synonymsprotein tyrosine phosphatase, placental; protein-tyrosine phosphatase 1B; PTP1B; tyrosine-protein phosphatase non-receptor type 1
- IsotypeIgG
- Protein IDP18031
- Protein NameTyrosine-protein phosphatase non-receptor type 1
- Scientific DescriptionTyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203