Western Blot Positive WB detected in: Jurkat whole cell lysate, 293 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate, K562 whole cell lysate All lanes: PTPN11 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69, 53 kDa Observed band size: 69 kDa
Western Blot Positive WB detected in: Jurkat whole cell lysate, 293 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate, K562 whole cell lysate All lanes: PTPN11 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69, 53 kDa Observed band size: 69 kDa
PTPN11 Recombinant Monoclonal Antibody
CSB-RA779218A0HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPTPN11
Overview
- SupplierCusabio
- Product NamePTPN11 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID7A1
- ConjugateUnconjugated
- Gene ID5781
- Target namePTPN11
- Target descriptionprotein tyrosine phosphatase non-receptor type 11
- Target synonymsBPTP3; CFC; JMML; METCDS; NS1; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; PTP-1D; PTP2C; SH2 domain-containing protein tyrosine phosphatase 2; SHP2; SH-PTP2; SH-PTP3; tyrosine-protein phosphatase non-receptor type 11
- IsotypeIgG
- Protein IDQ06124
- Protein NameTyrosine-protein phosphatase non-receptor type 11
- Scientific DescriptionActs downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203