PTPN18 Polyclonal Antibody
RD267993A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetPTPN18
Overview
- SupplierReddot Biotech
- Product NamePTPN18 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID26469
- Target namePTPN18
- Target descriptionprotein tyrosine phosphatase non-receptor type 18
- Target synonymsBDP1; brain-derived phosphatase; protein tyrosine phosphatase, non-receptor type 18 (brain-derived); PTP-HSCF; tyrosine-protein phosphatase non-receptor type 18
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203