Western blot analysis of extracts from HeLa/Jurkat cells, using PTPN22 antibody.
Western blot analysis of extracts from HeLa/Jurkat cells, using PTPN22 antibody.
PTPN22 Antibody
CSB-PA780242
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPTPN22
Overview
- SupplierCusabio
- Product NamePTPN22 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID26191
- Target namePTPN22
- Target descriptionprotein tyrosine phosphatase non-receptor type 22
- Target synonymshematopoietic cell protein-tyrosine phosphatase 70Z-PEP; lymphoid-specific protein tyrosine phosphatase; LYP; LYP1; LYP2; PEP; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; PTPN22.5; PTPN22.6; PTPN8; tyrosine-protein phosphatase non-receptor type 22
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y2R2
- Protein NameTyrosine-protein phosphatase non-receptor type 22
- Scientific DescriptionActs as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules. Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating Tyr-394 residue. Dephosphorylates ZAP70 at its activating Tyr-493 residue. Dephosphorylates the immune system activator SKAP2. Cohen S., Blood 93:2013-2024(1999). Liu T., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases. Wang S., Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203