PTPN22 Polyclonal Antibody
RD81698A
TargetPTPN22
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NamePTPN22 Polyclonal Antibody
- Delivery Days Customer5
- Concentration1 mg/ml
- Gene ID26191
- Target namePTPN22
- Target descriptionprotein tyrosine phosphatase non-receptor type 22
- Target synonymshematopoietic cell protein-tyrosine phosphatase 70Z-PEP; lymphoid-specific protein tyrosine phosphatase; LYP; LYP1; LYP2; PEP; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; PTPN22.5; PTPN22.6; PTPN8; tyrosine-protein phosphatase non-receptor type 22
- Scientific DescriptionThis gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
- Storage Instruction-20°C
- UNSPSC12352203