PTPRN Polyclonal Antibody

Reddot Biotech

PTPRN Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.96 mg/ml

Unconjugated

PTPRN

protein tyrosine phosphatase receptor type N

IA2; IA-2; IA-2/PTP; ICA 512; ICA512; insulinoma-associated tyrosine-phosphatase-like protein; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase-like N; PTP IA-2; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N

Rabbit

IgG

IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.

Human, Mouse, Rat

-20°C

12352203