PTPRN2 Polyclonal Antibody

Reddot Biotech

PTPRN2 Polyclonal Antibody

5

1 mg/ml

PTPRN2

protein tyrosine phosphatase receptor type N2

IA-2beta; IAR; IAR/receptor-like protein-tyrosine phosphatase; ICAAR; islet cell autoantigen-related protein; phogrin; protein tyrosine phosphatase receptor pi; protein tyrosine phosphatase, receptor type, N polypeptide 2; PTPRP; receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; tyrosine phosphatase IA-2 beta

This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.

-20°C

12352203