![PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL [26628-22-8] PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2018/10/BNUB2146.jpeg)
PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC402146
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetSPI1
Overview
- SupplierBiotium
- Product NamePU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPU1/2146
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID6688
- Target nameSPI1
- Target descriptionSpi-1 proto-oncogene
- Target synonyms31 kDa transforming protein; hematopoietic transcription factor PU.1; OF; PU.1; SFPI1; SPI-1; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene spi1; transcription factor PU.1
- HostMouse
- IsotypeIgG2b
- Protein IDP17947
- Protein NameTranscription factor PU.1
- Scientific DescriptionPU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203