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PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL [26628-22-8]

PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC402146
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetSPI1
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Overview

  • Supplier
    Biotium
  • Product Name
    PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PU1/2146
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID6688
  • Target name
    SPI1
  • Target description
    Spi-1 proto-oncogene
  • Target synonyms
    31 kDa transforming protein; hematopoietic transcription factor PU.1; OF; PU.1; SFPI1; SPI-1; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene spi1; transcription factor PU.1
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP17947
  • Protein Name
    Transcription factor PU.1
  • Scientific Description
    PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203