(R,R)-PX20606

MedChem Express

(-)-PX20606 (trans isomer) [1268244-88-7]

10

1268244-88-7

C29H22Cl3NO4

554.85

(R,R)-PX20606 is a FXR agonist with EC 50 s of 18 and 29 nM for FXR in FRET and M1H assay, respectively.

ClC1=C(C2=NOC(C3CC3)=C2COC4=CC=C([C@@H]5C[C@H]5C6=CC=C(C(O)=O)C=C6)C(Cl)=C4)C(Cl)=CC=C1

-20°C,2°C to 8°C

12352200