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Pyrene phosphoramidite dU

Pyrene phosphoramidite dU

A270252
Antibodies.com
Estimated Purity95%
Product group Chemicals
Molecular Weight955.04 kDa
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Overview

  • Supplier
    Antibodies.com
  • Product Name
    Pyrene phosphoramidite dU
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    95%
  • Molecular Formula
    C57H55N4O8P
  • Molecular Weight
    955.04 kDa
  • Scientific Description
    Pyrene is polycyclic aromatic hydrocarbon which is well-known for its ability to intercalate into DNA. Pyrene features intense blue fluorescence. Its parameters depend strongly on fluorophore microenvironment. Therefore, fluorescence spectra of pyrene are used for the extraction of structural information about site surrounding pyrene. Two pyrenes in close proximity usually form excimers easily detectable by excimer fluorescence. Pyrene can also be a FRET donor to other fluorophores such as perylene. With this phosphoramidite, pyrene can be introduced into DNA by means of automated synthesis. This pyrene phosphoramidite contains hydrocarbon moiety rigidly attached to deoxyuridine. This reagent allows the attachment of a pyrene fragment to 5, internal, or 3 positions (using universal support). This amidite requires no special handling, coupling, or deprotection conditions. Recommended diluent for it is acetonitrile.
  • UNSPSC
    41116134