Pyruvate dehydrogenase kinase 1 / PDK1 blocking peptide

GeneTex

Pyruvate dehydrogenase kinase 1 / PDK1 blocking peptide

9

Research Use Only

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

-20°C or -80°C,2°C to 8°C

12352202