QAQ (dichloride)

MedChem Express

QAQ (dichloride)

10

Research Use Only

99.30

C28H44Cl2N6O2

567.59

QAQ dichloride, a photoswitchable voltage-gated Na v and K v channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain [1] [2] .

O=C(NC1=CC=C(/N=N/C2=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C2)C=C1)C[N+](CC)(CC)CC.[Cl-].[Cl-]

2°C to 8°C

12352200