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ProductsBack/QL-X-138 [1469988-63-3]
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CgoaEWY7RMGEam0ZAAAAAD5fpDg487.png
CgoaEWY7RMGEam0ZAAAAAD5fpDg487.png

QL-X-138 [1469988-63-3]

Research Use Only
T38960
TargetMol Chemicals
CAS Number1469988-63-3
DownloadMSDS
Product group Chemicals
Molecular Weight421.45
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    QL-X-138 [1469988-63-3]
  • Delivery Days Customer
    10
  • CAS Number
    1469988-63-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    QL-X-138
  • Molecular Formula
    C25H19N5O2
  • Molecular Weight
    421.45
  • Scientific Description
    QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK. The IC50 values of QL-X-138 are 9.4 nM for BTK, 107.4 nM for MNK1, 26 nM for MNK2, and 3.5 microM against Dengue 2. QL-X-138 is used in the study of B-cell malignancies and B-cell malignant tumors.
  • Shelf life instruction
    3 years
  • SMILES
    O=C1N(C2=C3C(=NC=C2C=C1)C=CC(=C3)C=4C=NNC4)C5=CC(NC(C=C)=O)=C(C)C=C5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Wu H, et, al. Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia. Leukemia. 2016 Jan;30(1):173-81.
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