Quetiapine-d4-1 (fumarate)

MedChem Express

Quetiapine-d4-1 (fumarate)

5

Research Use Only

C21H21D4N3O2S.1/2C4H4O4

445.57

Quetiapine-d 4 -1 fumarate is deuterated labeled Quetiapine (hemifumarate) (HY-B0031). Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC 50 of 4.77 for human 5-HT1A receptor . Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC 50 of 6.33 for human D2 receptor . Quetiapine hemifumarate has moderate to high affinity for the human D2 , HT1A , 5-HT2A , 5-HT2C receptor with pK i s of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects [1] .

OC([2H])([2H])C([2H])([2H])OCCN(CC1)CCN1C2=NC3=CC=CC=C3SC4=C2C=CC=C4.O=C(O)/C=C/C(O)=O.[0.5]

12352200