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Quiflapon

HY-10037
MedChem Express
CAS Number136668-42-3
Product group Chemicals
Estimated Purity99.84
Molecular Weight587.17
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Quiflapon [136668-42-3]
  • Delivery Days Customer
    10
  • CAS Number
    136668-42-3
  • Estimated Purity
    99.84
  • Molecular Formula
    C34H35ClN2O3S
  • Molecular Weight
    587.17
  • Scientific Description
    Quiflapon (MK-591) is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC 50 ?of 1.6 nM in a FLAP binding assay. Quiflapon is also a potent and orally active? Leukotriene biosynthesis (LT) ?inhibitor, shows IC 50 ?values of 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively. Quiflapon induces cell apoptosis [1] [2] .
  • SMILES
    O=C(O)C(C)(C)CC1=C(SC(C)(C)C)C2=C(C=CC(OCC3=NC4=CC=CC=C4C=C3)=C2)N1CC5=CC=C(Cl)C=C5
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200