(R)-8-Azido-2-(Fmoc-amino)octanoic acid [1191429-18-1]

MedChem Express

(R)-8-Azido-2-(Fmoc-amino)octanoic acid [1191429-18-1]

10

1191429-18-1

Research Use Only

C23H26N4O4

422.48

(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

OC([C@@H](CCCCCCN=[N+]=[N-])NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O

41115800