(R)-8-Azido-2-(Fmoc-amino)octanoic acid

MedChem Express

(R)-8-Azido-2-(Fmoc-amino)octanoic acid [1191429-18-1]

10

Research Use Only

(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1] . (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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