(R)-AMG-193

MedChem Express

(R)-AMG-193

5

Research Use Only

98.53

(R)-AMG-193 is an isomer of AMG 193 (HY-153390). AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. AMG 193, when complexed with MTA, preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5 (IC50=0.107 microM), thereby protecting normal cells with wild-type MTAP[1][2].

-20°C,2°C to 8°C

12352200