(R)-BMS-816336

MedChem Express

(R)-BMS-816336

10

1009583-83-8

Research Use Only

96.57

C21H27NO3

341.44

(R)-BMS-816336 (Compound 6n-1) is a potent and orally active inhibitor of human , mouse and cynomolgus monkey 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) enzyme with IC 50 s of 14.5 nM, 50.3 nM and 16 nM, respectively [1] .

O[C@H]1[C@H]2C[C@@H]3[C@@](C4=CC=CC=C4)(CC(N5CC(O)C5)=O)[C@@H](C[C@H]1C3)C2

-20°C,2°C to 8°C

12352200