(R)-DPN

MedChem Express

(R)-DPN

5

524047-78-7

Research Use Only

C15H13NO2

239.27

(R)-DPN (compound 3) is a selective ERbeta ligand with EC 50 s of 2.9, 0.8 nM for ERalpha and ERbeta, respectively. (R)-DPN shows a very high affinity and potency preference for ERbeta over ERalpha. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC 50 s of 286, 205 nM, respectively [1] .

N#C[C@@H](C(C=C1)=CC=C1O)CC(C=C2)=CC=C2O

12352200