(R)-(-)-Gossypol acetic acid [866541-93-7]
S2812
CAS Number866541-93-7
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product Name(R)-(-)-Gossypol acetic acid [866541-93-7]
- Delivery Days Customer9
- CAS Number866541-93-7
- CertificationResearch Use Only
- Scientific Description(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 muM, 0.48 muM and 0.18 muM in cell-free assays; does not inhibit BIR3 domain and BID. AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy. Phase 2.
- UNSPSC12352200
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