(R)-Phe-A110/B319

MedChem Express

(R)-Phe-A110/B319

14

Research Use Only

C62H57F3N8O14S

1227.22

(R)-Phe-A110/B319, a hapten, is a selective binder to tumor-associated antigens. (R)-Phe-A110/B319 has a 20-fold higher affinity towards the H1047R mutant of p110alpha in the p110alpha/p85alpha PI3K complex. (R)-Phe-A110/B319 can be used for the research of conditional chimeric antigen receptor T (CAR-T) cell activation and tumor targeting[1].

O=C(NCCC(N[C@H](CC(N[C@H](CCCCNC(NC(C=C1)=CC(C(O2)=O)=C1C32C4=C(OC5=CC(O)=CC=C53)C=C(C=C4)O)=S)C(O)=O)=O)C(O)=O)=O)[C@H](NC(C6=CC=C7N=C(C(C)=NC7=C6)C)=O)CC8=CC=C(C=C8)C9=CC=C(C=C9C)OC(F)(F)F

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