(R)-Pralatrexate

MedChem Express

(R)-Pralatrexate

14

Research Use Only

C23H23N7O5

477.47

(R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor[1].

O=C(CC[C@H](NC(C1=CC=C(C=C1)[C@H](CC#C)CC2=NC3=C(N=C(N=C3N=C2)N)N)=O)C(O)=O)O

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