(R)-STU104

MedChem Express

(R)-STU104

10

Research Use Only

99.91

C18H18O4

298.33

(R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC50s of 0.58 microM and 4.0 microM for TNF-alpha and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis[1].

O=C1C[C@H](C2=CC=C(OC)C=C2)C3=C1C=C(OC)C=C3OC

-20°C

12352200