R112 [575474-82-7]
HY-16420
Overview
- SupplierMedChem Express
- Product NameR112 [575474-82-7]
- Delivery Days Customer10
- CAS Number575474-82-7
- CertificationResearch Use Only
- Estimated Purity99.71
- Molecular FormulaC16H13FN4O2
- Molecular Weight312.30
- Scientific DescriptionR112 is a fast and reversible inhibitor of spleen tyrosine kinase (Syk) kinase. R112 inhibits Syk kinase activity with an IC50 value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcepsilonRI signaling pathway. R112 can be used for the research of allergic rhinitis[1].
- SMILESFC1=CN=C(NC2=CC(O)=CC=C2)N=C1NC3=CC(O)=CC=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200