R18

MedChem Express

R18 [211364-78-2]

10

Research Use Only

R18 is a peptide antagonists of 14-3-3 , with a K D of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1 [1] .

12352202