Chemical Structure
Chemical Structure
R428 [1037624-75-1]
SYN-1131
CAS Number1037624-75-1
Product group Chemicals
Estimated Purity>95%
Molecular Weight506.6
Overview
- SupplierSYNkinase
- Product NameR428 [1037624-75-1]
- Delivery Days Customer10
- CAS Number1037624-75-1
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC30H34N8
- Molecular Weight506.6
- Scientific DescriptionChemical. CAS: 1037624-75-1. Formula: C30H34N8. MW: 506.6. R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM . - R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352200