
Western blot analysis of extracts from HeLa cells and HepG2 cells, using RAB31 antibody.
RAB31 Antibody
CSB-PA139202
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAB31
Overview
- SupplierCusabio
- Product NameRAB31 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11031
- Target nameRAB31
- Target descriptionRAB31, member RAS oncogene family
- Target synonymsRab22B; ras-related protein Rab-22B; ras-related protein Rab-31
- HostRabbit
- IsotypeIgG
- Protein IDQ13636
- Protein NameRas-related protein Rab-31
- Scientific DescriptionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Chen D., Gene 174:129-134(1996) [PubMed: 8863739]. Bao X.,Eur. J. Biochem. 269:259-271(2002) [PubMed: 11784320]. Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203