Rabbit anti Human FAN, N-SMase Activation Associated Factor
X2355P
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetNSMAF
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human FAN, N-SMase Activation Associated Factor
- Delivery Days Customer7
- Application Supplier NoteAntibody can be used for Western blotting (1-5 microg/ml). Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot
- Applications SupplierWestern Blotting;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8439
- Target nameNSMAF
- Target descriptionneutral sphingomyelinase activation associated factor
- Target synonymsfactor associated with neutral sphingomyelinase activation; factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; protein FAN
- HostRabbit
- Protein IDQ8IW26
- Protein NameProtein FAN
- Scientific DescriptionFAN (Factor associated with neutral sphingomyelinase activation) SMAF; Neutral sphingomyelinase (N-SMase) activation associated factor
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteSynthetic peptide derived from human NSMAF protein.
- UNSPSC12352203
References
- 1. O’Brien, N.W., et al. 'Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death.' Circ Res. 2003 Apr 4;92(6):589-91. 2. Segui, B., et al. 'CD40 Signals apoptosis through FAN-regulated activation of the sphinogmyelin-ceramide pathway.' J Biol Chem. 1999; 274: 37251–37258 3. Adam-Klages, S., et al. 'FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase.' Cell. 1996; 86: 937–947. 4. Segui, B., et al. 'Involvement of FAN in TNF-induced apoptosis.' J Clin Invest. 2001; 108: 143–151.