Rabbit anti Human PINK1
X2764P
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPINK1
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human PINK1
- Delivery Days Customer7
- Application Supplier NoteOptimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- Applications SupplierWestern Blotting;Enzyme Immunoassay;Western Blotting;Immunohistochemistry;Enzyme Immunoassay
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- Gene ID65018
- Target namePINK1
- Target descriptionPTEN induced kinase 1
- Target synonymsBRPK; PARK6; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; serine/threonine-protein kinase PINK1, mitochondrial
- HostRabbit
- IsotypeIgG
- Protein IDQ9BXM7
- Protein NameSerine/threonine-protein kinase PINK1, mitochondrial
- Scientific DescriptionPTEN-induced putative kinase protein 1
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteSynthetic peptide derived from the human PINK1 protein. Control for antibody to E417G mutant (Cat. No. X2763P)
- UNSPSC12352203
References
- 1. Matsuda, N., et al. ‘PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.’ J. Cell. Biol., 189, 211-221 (2010) 2. Vives-Bauza, C., et al. ‘PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.’ Proc. Natl. Acad. Sci. USA, 107, 378-383 (2010) 3. Valente, E.M., et al. ‘PINK1 mutations are associated with sporadic early-onset parkinsonism.’ Ann. Neurol., 56, 336-341 (2004) 4. Geisler, S., et al. ‘The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations.’ Autophagy, 6, 871-878 (2010) 5. Valente, E.M., et al. ‘Hereditary early-onset Parkinson's disease caused by mutations in PINK1.’ Science, 304, 1158-1160 (2004) 6. Silvestri, L., et al. ‘Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.’ Hum. Mol. Genet., 14, 3477-3492 (2005)