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ProductsBack/Rabbit anti Human SMO (Smoothened Homolog)

Rabbit anti Human SMO (Smoothened Homolog)

Research Use Only
X2376P
Nordic-MUbio
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetSMO
Price on request
100 ug
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More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Rabbit anti Human SMO (Smoothened Homolog)
  • Delivery Days Customer
    7
  • Application Supplier Note
    Antibody can be used for Western blotting (1-5microg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot
  • Applications Supplier
    Western Blotting;Western Blotting
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID6608
  • Target name
    SMO
  • Target description
    smoothened, frizzled class receptor
  • Target synonyms
    CRJS; frizzled family member 11; FZD11; Gx; PHLS; protein Gx; seven transmembrane helix receptor; SMOH; smoothened homolog; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ99835
  • Protein Name
    Smoothened homolog
  • Scientific Description
    Smoothened homolog [Precursor], SMO, Gx protein, SMO, SMOH
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Synthetic peptide derived from the human SMO protein
  • UNSPSC
    12352203

References

  • 1. Stone, D.M., et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.; Nature 384:129-134(1996). 2. Xie, J., et al. Activating Smoothened mutations in sporadic basal-cell carcinoma.; Nature 391:90-92(1998). 3. Liu, Y., et al. 'Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation.' Genes Dev. 2007 Aug 1;21(15):1949-63. 4. Moraea, R.C., et al. 'Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.' Development. 2007 Mar;134(6):1231-42. 5. Ruiz-Gomez, A., et al. 'The cell biology of Smo signalling and its relationships with GPCRs.' Biochim Biophys Acta. 2007 Apr;1768(4):901-12.