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The data was published in the journal Int J Mol Sci in 2018. PMID: 30042348
The data was published in the journal Int J Mol Sci in 2018. PMID: 30042348
The data was published in the journal Int J Mol Sci in 2018. PMID: 30042348

Rabbit IgG isotype control

GTX35035
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Rabbit IgG isotype control
  • Delivery Days Customer
    9
  • Application Supplier Note
    Use at a concentration/dilution equivalent to that of your experimental primary antibody.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress.
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  • HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease.
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  • Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity.
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  • MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10.
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  • Characterization of a new CCCTC-binding factor binding site as a dual regulator of Epstein-Barr virus latent infection.
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  • The interplay between the airway epithelium and tissue macrophages during the SARS-CoV-2 infection.
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  • IkappaBaeta controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies.
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  • CTCF-Induced lncRNA C5orf66-AS1 Facilitates the Progression of Triple-Negative Breast Cancer via Sponging miR-149-5p to Up-Regulate CTCF and CTNNB1 to Activate Wnt/beta-Catenin Pathway.
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  • K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy. Wang YT et al., 2022 Feb 22, Cell Rep
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  • Roles of ERRalpha and TGF-beta signaling in stemness enhancement induced by 1 microM bisphenol A exposure via human neural stem cells. Dong P et al., 2022 Feb, Exp Ther Med
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