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Rabusertib (LY2603618)

S2626
Selleck Chemicals
CAS Number911222-45-2
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Rabusertib (LY2603618) [911222-45-2]
  • Delivery Days Customer
    9
  • CAS Number
    911222-45-2
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Rabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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