Rabusertib (LY2603618)
S2626
CAS Number911222-45-2
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameRabusertib (LY2603618) [911222-45-2]
- Delivery Days Customer9
- CAS Number911222-45-2
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionRabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.
- Storage Instruction-80°C
- UNSPSC51202000