(Rac)-AMG8379

MedChem Express

(Rac)-AMG8379 [1641574-26-6]

10

1641574-26-6

Research Use Only

C25H16ClF2N3O5S

543.93

(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide antagonist of NaV1.7, with IC 50 s of 8.5 and 18.6 nM for hNaV1.7 and mNaV1.7, respectively [1] .

O=S(NC1=NOC=C1)(C2=CC(C=CC(N3C4=CC(F)=C(C=C4OC)C5=CC(Cl)=CC(F)=C5)=O)=C3C=C2)=O.[Racemate]

12352200