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Western Blot analysis of 293T, Hela, K562, NIH/3T3 and RAW264.7 cell using RAD50 Polyclonal Antibody at dilution of 1:900
Western Blot analysis of 293T, Hela, K562, NIH/3T3 and RAW264.7 cell using RAD50 Polyclonal Antibody at dilution of 1:900
Western Blot analysis of 293T, Hela, K562, NIH/3T3 and RAW264.7 cell using RAD50 Polyclonal Antibody at dilution of 1:900

RAD50 Polyclonal Antibody

E-AB-12632
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    RAD50 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.4mg/ml
  • Scientific Description
    The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
  • UNSPSC
    12352203