RAF1 antibody

Biorbyt

RAF1 antibody

16

Western Blot

WB:1:1000-1:5000 WB

Research Use Only

Polyclonal

Unconjugated

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

CMD1NN; CRAF; c-Raf; C-Raf proto-oncogene, serine/threonine kinase; NS5; Oncogene RAF1; proto-oncogene c-RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; Raf-1; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1

Rabbit

RAF proto-oncogene serine/threonine-protein kinase

Rabbit polyclonal to RAF1.RAF proto-oncogene serine/threonine-protein kinase AF1) belongs to the protein kinasesuperfamily. It acts as a regulatory link between the membrane-associated Ras GTPases and theMAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fatedecisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation.RAF1 can promote NF-kB activation and inhibit signal transducers involved in motility OCK2),apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis B1). It regulates Rhosignaling and migration, and is required for normal wound healing. Defects in RAF1 are the cause ofNoonan syndrome type 5 (NS5) and LEOPARD syndrome type 2 (LEOPARD2).

Human, Mouse

-20°C

12352203